SleepPhones work with nearly all personal audio devices. There are very few exceptions. SleepPhones have the standard 3.5mm plug.

First Generation iPhones with the recessed plug needs an adapter to work.	iPhone 3G and 3Gs will work fine, as will all other iPods, including nanos.
The newest Shuffles with the in-line earbud controls won't work with any other headphones.	The previous versions of Shuffles will work fine.